One contaminant class. Three EPA methods.
The right PFAS method is set by the matrix and the program: finished drinking water goes to EPA 533 (or 537.1 for legacy comparability), while wastewater, soil, and biosolids require EPA 1633; we run all three by isotope dilution so recovery is corrected analyte-by-analyte.
Published. Per-test.
No quote calls.
Every assay a la carte, every panel bundled. Bulk discount at 5+ samples. Prices below reflect a single-compound submission.
25-analyte + metals-ready reporting.
- EPA 533 (25-analyte)
- Six regulated analytes + UCMR 5
- ng/L vs federal MCL
- Public COA + accession #
18-analyte SPE.
- EPA 537.1 (18-analyte)
- SPE extraction
- State-program comparability
- Public COA + accession #
Wastewater / soil / biosolids / tissue.
- EPA 1633 (40-analyte)
- Wastewater / soil / biosolids / tissue
- NPDES & site-assessment ready
- Public COA + accession #
Where PFAS exceedances concentrate.
PFAS is everywhere at trace level, but regulatory exceedances cluster around a handful of source types; matching the method to the matrix is how you find them without chasing background noise.
SDWA NPDWR (2024), EPA 533 / 537.1 / 1633, UCMR 5, ISO 17025 Aligned.
PFAS regulation moved fast in 2024; the method and the limit both depend on which program governs your sample. Here's what we map to.
The April 2024 final rule set federal MCLs of 4 ng/L for PFOA and PFOS, 10 ng/L for PFNA, PFHxS, and HFPO-DA (GenX), plus a Hazard Index for the mixture; public water systems monitor by 2027 and comply by 2029. We report against the MCL on every drinking-water COA.
25-analyte direct-injection LC-MS/MS — the method most utilities use today, with labeled-surrogate recovery correction analyte-by-analyte.
18-analyte solid-phase-extraction method, retained for legacy comparability and state monitoring programs that pre-date EPA 533.
The 2024 final method covering 40 PFAS across wastewater, surface water, groundwater, soil, sediment, biosolids, and tissue — the reference for NPDES permits, Superfund work, and industrial-discharge characterization.
The fifth Unregulated Contaminant Monitoring Rule requiring nationwide PFAS occurrence data from public water systems (2023–2025), reported by EPA 533/537.1.
EPA 533 and 537.1 are drinking-water methods — 533 uses isotope-dilution direct injection (25 analytes, what most utilities use now), 537.1 uses SPE extraction (18 analytes, kept for legacy comparability). EPA 1633 is the multi-matrix method for wastewater, soil, biosolids, and tissue (40 analytes). We run all three and can do more than one on the same project.