The five numbers a GLP-1 buyer actually needs.
Identity tells you it's the right molecule. Purity tells you how clean it is. But for an incretin peptide sold by milligram, the questions that decide dose accuracy and injection tolerance are Net Peptide Content and TFA residual — and the injectable-grade questions are endotoxin and sterility. We run all of them on one bench, on one COA.
Published. Per-test.
No quote calls.
Every assay a la carte, every panel bundled. Bulk discount at 5+ samples. Prices below reflect a single-compound submission.
GLP-1 base — Identity + Purity + Net Content
Semaglutide, Tirzepatide, Retatrutide, Liraglutide, Cagrilintide, Survodutide — incretin-class identity, purity, and net content.
- Identity (LC-MS/MS)
- HPLC purity %
- Net Peptide Content (mg per vial)
- TFA / acetate residual
- Public COA + accession #
The base plus USP <85> endotoxin (LAL) — the most-requested add for anything sold as injectable-grade.
- Everything in GLP-1 Standard
- Endotoxin (LAL, USP <85>)
- Numeric EU/mL result
- 5–7 business days
Two lots of the same analog, individually tested and reported side-by-side — vendor-vs-vendor or lot-vs-lot.
- Two vials, individually tested
- Side-by-side COA
- NPC + purity delta called out
- Sourcing decision in one report
Injectable-grade bundles
GLP-1 base + Endotoxin (USP <85>) + Sterility (USP <71>). The injectable-grade package.
- Everything in GLP-1 Standard
- Endotoxin (LAL, USP <85>)
- Sterility (USP <71>)
- Public COA + accession #
GLP-1 base + Endotoxin + Heavy Metals + Sterility + Bioburden — every safety assay on one COA.
- Everything in Injectable Safety
- Heavy metals (ICP-MS, USP <232>)
- Bioburden (USP <61>)
- 5–7 day turnaround
Vendor Full QC on 3 vials of the same SKU, individually tested and batch-averaged for a production lot release.
- Vendor Full QC scope
- 3 vials individually tested
- Batch-averaged result
- Extra conformity vials $75 each
À-la-carte add-ons (flat, any GLP-1 base)
Kinetic chromogenic LAL with inhibition / enhancement validation. Numeric EU/mL result.
- USP <85> kinetic chromogenic
- Numeric EU/mL result
- Standard-curve r² documentation
Membrane filtration, 14-day media incubation. Required for terminally-sterilized injectables.
- USP <71> membrane filtration
- 14-day incubation
- Pass / fail + growth log
As, Cd, Pb, Hg (4-element) per USP <232>/<233> permitted-daily-exposure limits.
- ICP-MS, 4-element
- USP <232>/<233> PDE limits
- Numeric µg/g result
Every incretin analog, one bench.
Each GLP-1 analog has its own monoisotopic mass, its own characteristic synthesis impurities, and its own failure modes. Pass rates below reflect the share of submitted lots that cleared every ordered assay — under-dosing (low NPC) is the single most common flag.
USP, ICH, and data integrity for the incretin class.
Research and compounded GLP-1 testing sits outside the FDA finished-drug loop, but USP and ICH standards still anchor the analytical methods. Here is what each assay maps to.
LAL methodology for endotoxin quantitation — kinetic chromogenic on the Charles River Endosafe stack with documented inhibition / enhancement validation. Required for any GLP-1 intended for injectable / parenteral use.
Membrane filtration or direct inoculation into fluid thioglycollate and soybean-casein digest media, 14-day incubation. Required for terminally-sterilized injectable GLP-1 preparations and compounded vials.
Permitted Daily Exposure limits for Pb, Cd, As, Hg in pharmaceutical-grade material. Available as the heavy-metal scan add-on or bundled into Vendor Full QC.
ICH thresholds for reporting, identification, and qualification of impurities. Our HPLC method reports any impurity peak above 0.1 % area; impurities above 0.5 % get individual MS identification — the truncations and deletions specific to each incretin analog.
Instrument software audit trails, raw chromatograms, and mass spectra retained per 21 CFR Part 11-style data-integrity principles. Available to the client of record, and publishable alongside the COA at your option.
Yes — the GLP-1 / incretin class is our single most-requested category. Every GLP-1 base includes HPLC purity, LC-MS identity, Net Peptide Content, and TFA / acetate residual on one public COA. Endotoxin (USP <85>) and sterility (USP <71>) are available as add-ons or bundled for injectable-grade lots.
Pair this panel with —
Ozempic / Wegovy active — HPLC purity, m/z 4113.58 identity, NPC, TFA, endotoxin.
Mounjaro / Zepbound active — dual-agonist identity at m/z 4813.45, purity, and net content.
Every research peptide beyond the incretin class — same dual-method bench, same public COA.